Obese patients given Meridia should be in the range of more than 30 in terms of body mass index. The basic mechanism of action of this medication is to prevent the reuptake of neurotransmitters present at the nerve endings. Sibutramine is a drug that saves dopamine, norepinephrine, and serotonin from reuptake at nerve synapse. Such action of this medication may cause changes in the nerve signals and interactions with other nerves. Meridia comes in capsule form with a strength of 5 mg, 10 mg, and 15 mg of Sibutramine hydrochloride monohydrate. The reason behind its withdrawal from the market is its weight loss assisted action causing a high level of blood lipids.
Meridia is a drug that supports people in reducing their extra weight along with proper diet and exercises. Simply, Sibutramine hydrochloride monohydrate or Meridia is a drug of choice in the management of obesity. This medication has been currently withdrawn from the market voluntarily as to its weight loss and maintenance action of weight loss action results in cardiovascular problems like attack and strokes.
Sibutramine hydrochloride monohydrate or Meridia is risky for patients who are on medications like Selective Serotonin Reuptake Inhibitors (SSRIs) like fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), or Monoamine oxidase inhibitor (MAOs). Apart from this medication is not recommended for the patient on antibiotics therapy of ketoconazole (Nizoral), cimetidine (Tagamet), and erythromycin.